Influence of blood specimen collection method on various preanalytical sample quality indicators
نویسندگان
چکیده
منابع مشابه
Preanalytical errors in hospitals Implications for quality improvement of blood sample collection
...........................................................................................1 LIST OF ABBREVIATIONS .....................................................................2 ORIGINAL ARTICLES.............................................................................3 PROLOGUE ...........................................................................................4 BACKGROUND......
متن کاملRole of specimen collection in preanalytical variation of metalloproteinases and their inhibitors in blood.
bound iron. We now use the Unimate method as our routine method. With this method, serum iron is determined linearly up to 180 jmol1L and the detection limit is 0.9 j.tmol/L. Withinrun CVs are 0.4% (iron concentration, 7.7-38.0 j.tmoVL) and the analytical recoveries of added iron are 99.2-101.2%. We think that this colorimetric method, which does not involve sample deproteinization or heating, ...
متن کاملPreanalytical issues related to blood sample mixing
INTRODUCTION Homogeneity of sample achieved by adequate mixing of the blood sample is the key to the quality of analytical results. Immediate mixing of the sample upon blood collection insures that the anticoagulant in the specimen container has fully dissolved with the blood, thus maintaining not only the effective anticoagulant-to-blood ratio but also providing a specimen free from any blood ...
متن کاملDependence of TIMP-1 plasma levels on preanalytical specimen handling.
BACKGROUND Tissue inhibitor of metalloproteinases-1 (TIMP-1) in blood might be a helpful biomarker in various diseases. However, various authors report that TIMP-1 is dependent on preanalytical procedures. Our study was performed to determine how storage conditions and time to centrifugation influence TIMP-1. MATERIALS AND METHODS Twenty-six blood specimens were collected from each of 20 volu...
متن کاملPreanalytical aspects and sample quality assessment in metabolomics studies of human blood.
BACKGROUND Metabolomics is a powerful tool that is increasingly used in clinical research. Although excellent sample quality is essential, it can easily be compromised by undetected preanalytical errors. We set out to identify critical preanalytical steps and biomarkers that reflect preanalytical inaccuracies. METHODS We systematically investigated the effects of preanalytical variables (bloo...
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ژورنال
عنوان ژورنال: Indian Journal of Clinical Biochemistry
سال: 2008
ISSN: 0970-1915,0974-0422
DOI: 10.1007/s12291-008-0032-4